General Information

  • ID:  hor000471
  • Uniprot ID:  NA
  • Protein name:  Allatostatin B
  • Gene name:  NA
  • Organism:  Diploptera punctata
  • Family:  Allatostatin family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  NA
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  AYSYVSEYKRLPVYSFGL
  • Length:  18
  • Propeptide:  NA
  • Signal peptide:  NA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Stimulate juvenile hormone synthesis during metamorphosis;visceral muscle contractions
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor000471_AF2.pdbhor000471_ESM.pdb

Physical Information

Mass: 244582 Formula: C103H148N22O28
Absent amino acids: CDHIMNQTW Common amino acids: Y
pI: 8.98 Basic residues: 2
Polar residues: 8 Hydrophobic residues: 6
Hydrophobicity: -5 Boman Index: -1439
Half-Life: 4.4 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 81.11
Instability Index: 5546.67 Extinction Coefficient cystines: 5960
Absorbance 280nm: 350.59

Literature

  • PubMed ID:  10545101
  • Title:  Reverse Physiology in Drosophila: Identification of a Novel Allatostatin-Like Neuropeptide and Its Cognate Receptor Structurally Related to the Mammalian Somatostatin/Galanin/Opioid Receptor Family